There are 446.48 miles from Buffalo to Lexington in southwest direction and 516 miles (830.42 kilometers) by car, following the I-90 W route.
Buffalo and Lexington are 7 hours 59 mins far apart, if you drive non-stop .
This is the fastest route from Buffalo, NY to Lexington, KY. The halfway point is Nankin, OH.
Buffalo, NY and Lexington, KY are in the same time zone (EDT). Current time in both locations is 7:12 am.
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