There are 279.41 miles from Buffalo to Philadelphia in southeast direction and 378 miles (608.33 kilometers) by car, following the US-15 S route.
Buffalo and Philadelphia are 6 hours 15 mins far apart, if you drive non-stop .
This is the fastest route from Buffalo, NY to Philadelphia, PA. The halfway point is Cogan Station, PA.
Buffalo, NY and Philadelphia, PA are in the same time zone (EDT). Current time in both locations is 6:53 pm.
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