There are 539.56 miles from Charlotte to Buffalo in north direction and 655 miles (1,054.12 kilometers) by car, following the I-79 N route.
Charlotte and Buffalo are 10 hours 12 mins far apart, if you drive non-stop .
This is the fastest route from Charlotte, NC to Buffalo, NY. The halfway point is Anmoore, WV.
Charlotte, NC and Buffalo, NY are in the same time zone (EDT). Current time in both locations is 6:13 am.
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