There are 374.98 miles from Cincinnati to Durham in southeast direction and 492 miles (791.80 kilometers) by car, following the I-64 E route.
Cincinnati and Durham are 8 hours 3 mins far apart, if you drive non-stop .
This is the fastest route from Cincinnati, OH to Durham, NC. The halfway point is Pax, WV.
Cincinnati, OH and Durham, NC are in the same time zone (EDT). Current time in both locations is 11:44 am.
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