There are 476.22 miles from Durham to Buffalo in north direction and 643 miles (1,034.81 kilometers) by car, following the I-85 N and US-15 route.
Durham and Buffalo are 10 hours 45 mins far apart, if you drive non-stop .
This is the fastest route from Durham, NC to Buffalo, NY. The halfway point is Funkstown, MD.
Durham, NC and Buffalo, NY are in the same time zone (EDT). Current time in both locations is 8:17 pm.
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