There are 388.74 miles from Milwaukee to Lexington in southeast direction and 462 miles (743.52 kilometers) by car, following the I-65 S route.
Milwaukee and Lexington are 7 hours 41 mins far apart, if you drive non-stop .
This is the fastest route from Milwaukee, WI to Lexington, KY. The halfway point is Colfax, IN.
Please note the time difference between Milwaukee, WI and Lexington, KY is 1 hour. The current time in Milwaukee is 6:25 pm and the current time in Lexington is 7:25 pm.
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