There are 343.18 miles from Needles to San Luis Obispo in west direction and 394 miles (634.08 kilometers) by car, following the I-40 and US-95 route.
Needles and San Luis Obispo are 6 hours 28 mins far apart, if you drive non-stop .
This is the fastest route from Needles, CA to San Luis Obispo, CA. The halfway point is Aerial Acres, CA.
Needles, CA and San Luis Obispo, CA are in the same time zone (PDT). Current time in both locations is 7:00 pm.
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