There are 39.42 miles from Pittsburgh to East Palestine in northwest direction and 50 miles (80.47 kilometers) by car, following the I-376 Business W route.
Pittsburgh and East Palestine are 58 minutes far apart, if you drive non-stop .
This is the fastest route from Pittsburgh, PA to East Palestine, OH. The halfway point is Macarthur, PA.
Pittsburgh, PA and East Palestine, OH are in the same time zone (EDT). Current time in both locations is 3:27 pm.
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