There are 2,155.42 miles from Reno to Winston-Salem in east direction and 2,588 miles (4,164.98 kilometers) by car, following the I-80 route.
Reno and Winston-Salem are 1 day 12 hours far apart, if you drive non-stop .
This is the fastest route from Reno, NV to Winston-Salem, NC. The halfway point is Odessa, NE.
Please note the time difference between Reno, NV and Winston-Salem, NC is 3 hours. The current time in Reno is 1:56 am and the current time in Winston-Salem is 4:56 am.
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