There are 1,428.69 miles from Rochester to Centennial in west direction and 1,604 miles (2,581.39 kilometers) by car, following the I-80 route.
Rochester and Centennial are 23 hours 51 mins far apart, if you drive non-stop .
This is the fastest route from Rochester, NY to Centennial, CO. The halfway point is Iowa City, IA.
Please note the time difference between Rochester, NY and Centennial, CO is 2 hours. The current time in Rochester is 5:16 pm and the current time in Centennial is 3:16 pm.
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