There are 346.64 miles from Saint Paul to Chicago in southeast direction and 398 miles (640.52 kilometers) by car, following the I-94 E route.
Saint Paul and Chicago are 5 hours 53 mins far apart, if you drive non-stop .
This is the fastest route from Saint Paul, MN to Chicago, IL. The halfway point is Mauston, WI.
Saint Paul, MN and Chicago, IL are in the same time zone (CDT). Current time in both locations is 2:02 am.
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