There are 233.15 miles from Saint Paul to Des Moines in south direction and 246 miles (395.90 kilometers) by car, following the I-35 S route.
Saint Paul and Des Moines are 3 hours 40 mins far apart, if you drive non-stop .
This is the fastest route from Saint Paul, MN to Des Moines, IA. The halfway point is Hanlontown, IA.
Saint Paul, MN and Des Moines, IA are in the same time zone (CDT). Current time in both locations is 8:56 pm.
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