There are 1,944.84 miles from San Francisco to Indianapolis in east direction and 2,271 miles (3,654.82 kilometers) by car, following the I-80 route.
San Francisco and Indianapolis are 1 day 7 hours far apart, if you drive non-stop .
This is the fastest route from San Francisco, CA to Indianapolis, IN. The halfway point is Cheyenne, WY.
Please note the time difference between San Francisco, CA and Indianapolis, IN is 3 hours. The current time in San Francisco is 6:31 am and the current time in Indianapolis is 9:31 am.
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