There are 218.60 miles from San Luis Obispo to American Canyon in northwest direction and 255 miles (410.38 kilometers) by car, following the US-101 N route.
San Luis Obispo and American Canyon are 4 hours 3 mins far apart, if you drive non-stop .
This is the fastest route from San Luis Obispo, CA to American Canyon, CA. The halfway point is Salinas, CA.
San Luis Obispo, CA and American Canyon, CA are in the same time zone (PDT). Current time in both locations is 5:22 pm.
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