There are 322.71 miles from Tallahassee to Port Saint Lucie in southeast direction and 370 miles (595.46 kilometers) by car, following the Florida's Turnpike route.
Tallahassee and Port Saint Lucie are 5 hours 27 mins far apart, if you drive non-stop .
This is the fastest route from Tallahassee, FL to Port Saint Lucie, FL. The halfway point is Ocala, FL.
Tallahassee, FL and Port Saint Lucie, FL are in the same time zone (EDT). Current time in both locations is 3:17 am.
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