There are 234.90 miles from Birmingham to Knoxville in northeast direction and 256 miles (411.99 kilometers) by car, following the I-59 route.
Birmingham and Knoxville are 4 hours 49 mins far apart, if you drive non-stop.
This is the fastest route from Birmingham, AL to Knoxville, TN. The halfway point is Trenton, GA.
Please note the time difference between Birmingham, AL and Knoxville, TN is 1 hour. The current time in Birmingham is 1:07 pm and the current time in Knoxville is 2:07 pm.
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