There are 1,032.37 miles from Buffalo to Sikeston in southeast direction and 1,291 miles (2,077.66 kilometers) by car, following the I-90 and US-14 E route.
Buffalo and Sikeston are 18 hours 17 mins far apart, if you drive non-stop .
This is the fastest route from Buffalo, WY to Sikeston, MO. The halfway point is Burbank, SD.
Please note the time difference between Buffalo, WY and Sikeston, MO is 1 hour. The current time in Buffalo is 11:18 pm (Mar 28) and the current time in Sikeston is 12:18 am (Mar 29).
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