There are 333.48 miles from Carbondale to Antioch in north direction and 387 miles (622.82 kilometers) by car, following the I-57 N route.
Carbondale and Antioch are 6 hours 27 mins far apart, if you drive non-stop .
This is the fastest route from Carbondale, IL to Antioch, IL. The halfway point is Savoy, IL.
Carbondale, IL and Antioch, IL are in the same time zone (CDT). Current time in both locations is 10:40 pm.
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