There are 49.93 miles from Carbondale to Cairo in south direction and 53 miles (85.30 kilometers) by car, following the US-51 S route.
Carbondale and Cairo are 1 hour 8 mins far apart, if you drive non-stop .
This is the fastest route from Carbondale, IL to Cairo, IL. The halfway point is Dongola, IL.
Carbondale, IL and Cairo, IL are in the same time zone (CDT). Current time in both locations is 11:50 pm.
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