There are 33.47 miles from Carbondale to Cape Girardeau in southwest direction and 46 miles (74.03 kilometers) by car, following the US-51 route.
Carbondale and Cape Girardeau are 1 hour 8 mins far apart, if you drive non-stop .
This is the fastest route from Carbondale, IL to Cape Girardeau, MO. The halfway point is Jonesboro, IL.
Carbondale, IL and Cape Girardeau, MO are in the same time zone (CDT). Current time in both locations is 10:18 pm.
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