There are 347.64 miles from Charleston to Mount Vernon in southwest direction and 383.73 miles (617.55 kilometers) by car, following the I-44 route.
Charleston and Mount Vernon are 5 hours 29 mins far apart, if you drive non-stop.
This is the fastest route from Charleston, IL to Mount Vernon, MO. The halfway point is .
Charleston, IL and Mount Vernon, MO are in the same time zone (CDT). Current time in both locations is 8:41 pm.
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