There are 252.16 miles from Chicago to Cincinnati in southeast direction and 291.03 miles (468.37 kilometers) by car, following the I-65 route.
Chicago and Cincinnati are 4 hours 46 mins far apart, if you drive non-stop.
This is the fastest route from Chicago, IL to Cincinnati, OH. The halfway point is .
Please note the time difference between Chicago, IL and Cincinnati, OH is 1 hour. The current time in Chicago is 9:21 am and the current time in Cincinnati is 10:21 am.
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