There are 393.08 miles from Cincinnati to Buffalo in northeast direction and 433.89 miles (698.28 kilometers) by car, following the I-90 route.
Cincinnati and Buffalo are 6 hours 4 mins far apart, if you drive non-stop.
This is the fastest route from Cincinnati, OH to Buffalo, NY. The halfway point is .
Cincinnati, OH and Buffalo, NY are in the same time zone (EDT). Current time in both locations is 6:38 am.
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