There are 410.24 miles from Des Moines to Indianapolis in southeast direction and 470 miles (756.39 kilometers) by car, following the I-74 and US-51 route.
Des Moines and Indianapolis are 8 hours 38 mins far apart, if you drive non-stop.
This is the fastest route from Des Moines, IA to Indianapolis, IN. The halfway point is Williamsfield, IL.
Please note the time difference between Des Moines, IA and Indianapolis, IN is 1 hour. The current time in Des Moines is 3:12 pm and the current time in Indianapolis is 4:12 pm.
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