There are 315.95 miles from Detroit to Louisville in southwest direction and 362 miles (582.58 kilometers) by car, following the I-75 route.
Detroit and Louisville are 7 hours 6 mins far apart, if you drive non-stop.
This is the fastest route from Detroit, MI to Louisville, KY. The halfway point is Piqua, OH.
Detroit, MI and Louisville, KY are in the same time zone (Eastern Daylight Time). Current time in both locations is 5:21 am.
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