There are 525.46 miles from Dover to Isle of Palms in southeast direction and 642 miles (1,033.20 kilometers) by car, following the I-40 route.
Dover and Isle of Palms are 10 hours 15 mins far apart, if you drive non-stop .
This is the fastest route from Dover, TN to Isle of Palms, SC. The halfway point is Newport, TN.
Please note the time difference between Dover, TN and Isle of Palms, SC is 1 hour. The current time in Dover is 4:24 am and the current time in Isle of Palms is 5:24 am.
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