There are 270.88 miles from Henderson to Fresno in west direction and 394 miles (634.08 kilometers) by car, following the Barstow-Bakersfield Highway route.
Henderson and Fresno are 5 hours 32 mins far apart, if you drive non-stop.
This is the fastest route from Henderson, NV to Fresno, CA. The halfway point is .
Henderson, NV and Fresno, CA are in the same time zone (PDT). Current time in both locations is 3:37 pm.
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