There are 789.72 miles from Houston to Knoxville in northeast direction and 923 miles (1,485.42 kilometers) by car, following the I-20 and I-59 and US-80 route.
Houston and Knoxville are 17 hours 4 mins far apart, if you drive non-stop.
This is the fastest route from Houston, TX to Knoxville, TN. The halfway point is Ellisville, MS.
Please note the time difference between Houston, TX and Knoxville, TN is 1 hour. The current time in Houston is 1:06 am and the current time in Knoxville is 2:06 am.
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