There are 789.72 miles from Houston to Knoxville in northeast direction and 924.98 miles (1,488.61 kilometers) by car, following the I-10 route.
Houston and Knoxville are 13 hours 19 mins far apart, if you drive non-stop.
This is the fastest route from Houston, TX to Knoxville, TN. The halfway point is .
Please note the time difference between Houston, TX and Knoxville, TN is 1 hour. The current time in Houston is 9:21 am and the current time in Knoxville is 10:21 am.
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