There are 252.06 miles from Huntsville to Puxico in northwest direction and 349 miles (561.66 kilometers) by car, following the US-72 Alternate and AL 20 route.
Huntsville and Puxico are 6 hours 8 mins far apart, if you drive non-stop .
This is the fastest route from Huntsville, AL to Puxico, MO.
Huntsville, AL and Puxico, MO are in the same time zone (CDT). Current time in both locations is 2:23 am.
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