There are 106.90 miles from Indianapolis to Louisville in southeast direction and 114.54 miles (184.33 kilometers) by car, following the I-65 route.
Indianapolis and Louisville are 1 hour 59 mins far apart, if you drive non-stop.
This is the fastest route from Indianapolis, IN to Louisville, KY. The halfway point is .
Indianapolis, IN and Louisville, KY are in the same time zone (EDT). Current time in both locations is 6:32 pm.
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