There are 256.05 miles from Jacksonville to Columbia in north direction and 290.65 miles (467.76 kilometers) by car, following the I-95 route.
Jacksonville and Columbia are 4 hours 4 mins far apart, if you drive non-stop.
This is the fastest route from Jacksonville, FL to Columbia, SC. The halfway point is .
Jacksonville, FL and Columbia, SC are in the same time zone (EDT). Current time in both locations is 6:45 am.
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