There are 256.05 miles from Jacksonville to Columbia in north direction and 291 miles (468.32 kilometers) by car, following the I-95 route.
Jacksonville and Columbia are 5 hours 18 mins far apart, if you drive non-stop.
This is the fastest route from Jacksonville, FL to Columbia, SC. The halfway point is Hardeeville, SC.
Jacksonville, FL and Columbia, SC are in the same time zone (Eastern Daylight Time). Current time in both locations is 4:35 am.
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