There are 225.49 miles from Jacksonville to Port Saint Lucie in southeast direction and 235 miles (378.20 kilometers) by car, following the FL 10 route.
Jacksonville and Port Saint Lucie are 4 hours 21 mins far apart, if you drive non-stop.
This is the fastest route from Jacksonville, FL to Port Saint Lucie, FL. The halfway point is Oak Hill, FL.
Jacksonville, FL and Port Saint Lucie, FL are in the same time zone (Eastern Daylight Time). Current time in both locations is 8:04 pm.
Any questions or tips to share?
Share with fellow travellers any question or tips about the route from Jacksonville, FL to Port Saint Lucie, FL: