There are 225.74 miles from Jacksonville to Port Saint Lucie in southeast direction and 238.99 miles by car, following the route.
Jacksonville and Port Saint Lucie are 3 hours 27 mins far apart, if you drive non-stop.
This is the fastest route from Jacksonville, FL to Port Saint Lucie, FL. The halfway point is .
Jacksonville, FL and Port Saint Lucie, FL are in the same time zone (EDT). Current time in both locations is 6:41 pm.
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