There are 343.68 miles from La Crosse to Alton in south direction and 483 miles (777.31 kilometers) by car, following the I-39 S and US-51 S route.
La Crosse and Alton are 7 hours 21 mins far apart, if you drive non-stop .
This is the fastest route from La Crosse, WI to Alton, IL. The halfway point is Mount Pleasant, IA.
La Crosse, WI and Alton, IL are in the same time zone (CDT). Current time in both locations is 2:12 pm.
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