There are 863.37 miles from La Crosse to Clayton in southeast direction and 1,077 miles (1,733.26 kilometers) by car, following the I-76 E and PATP E route.
La Crosse and Clayton are 16 hours 19 mins far apart, if you drive non-stop .
This is the fastest route from La Crosse, WI to Clayton, DE. The halfway point is Lemoyne, OH.
Please note the time difference between La Crosse, WI and Clayton, DE is 1 hour. The current time in La Crosse is 6:33 am and the current time in Clayton is 7:33 am.
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