There are 673.22 miles from La Crosse to Tupelo in southeast direction and 882 miles (1,419.44 kilometers) by car, following the I-55 S route.
La Crosse and Tupelo are 13 hours 18 mins far apart, if you drive non-stop .
This is the fastest route from La Crosse, WI to Tupelo, MS. The halfway point is Litchfield, IL.
La Crosse, WI and Tupelo, MS are in the same time zone (CDT). Current time in both locations is 9:34 pm.
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