There are 330.78 miles from Lakeland to Knoxville in east direction and 368 miles (592.24 kilometers) by car, following the I-40 route.
Lakeland and Knoxville are 5 hours 33 mins far apart, if you drive non-stop .
This is the fastest route from Lakeland, TN to Knoxville, TN. The halfway point is Melrose, TN.
Please note the time difference between Lakeland, TN and Knoxville, TN is 1 hour. The current time in Lakeland is 8:20 pm and the current time in Knoxville is 9:20 pm.
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