There are 332.12 miles from Louisville to Birmingham in south direction and 366 miles (589.02 kilometers) by car, following the I-65 route.
Louisville and Birmingham are 6 hours 40 mins far apart, if you drive non-stop.
This is the fastest route from Louisville, KY to Birmingham, AL. The halfway point is Melrose, TN.
Please note the time difference between Louisville, KY and Birmingham, AL is 1 hour. The current time in Louisville is 12:43 am (Nov 23) and the current time in Birmingham is 11:43 pm (Nov 22).
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