There are 332.12 miles from Louisville to Birmingham in south direction and 366 miles (589.02 kilometers) by car, following the I-65 S route.
Louisville and Birmingham are 5 hours 45 mins far apart, if you drive non-stop .
This is the fastest route from Louisville, KY to Birmingham, AL. The halfway point is Melrose, TN.
Please note the time difference between Louisville, KY and Birmingham, AL is 1 hour. The current time in Louisville is 8:13 am and the current time in Birmingham is 7:13 am.
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