There are 539 miles from Madison to Saint James in northeast direction and 642 miles (1,033.20 kilometers) by car, following the I-81 N route.
Madison and Saint James are 9 hours 42 mins far apart, if you drive non-stop.
This is the fastest route from Madison, TN to Saint James, MD. The halfway point is Emory, VA.
Please note the time difference between Madison, TN and Saint James, MD is 1 hour. The current time in Madison is 10:28 pm and the current time in Saint James is 11:28 pm.
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