There are 348.95 miles from Memphis to Knoxville in east direction and 387 miles (622.82 kilometers) by car, following the I-40 route.
Memphis and Knoxville are 7 hours 9 mins far apart, if you drive non-stop.
This is the fastest route from Memphis, TN to Knoxville, TN. The halfway point is Pegram, TN.
Please note the time difference between Memphis, TN and Knoxville, TN is 1 hour. The current time in Memphis is 12:56 pm and the current time in Knoxville is 1:56 pm.
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