There are miles from Mesa to Sioux Falls in northeast direction and miles by car, following the route.
Mesa and Sioux Falls are far apart, if you drive non-stop.
This is the fastest route from Mesa, AZ to Sioux Falls, SD. The halfway point is .
Please note the time difference between Mesa, AZ and Sioux Falls, SD is 2 hours. The current time in Mesa is 7:18 pm and the current time in Sioux Falls is 9:18 pm.
Any questions or tips to share?
Share with fellow travellers any question or tips about the route from Mesa, AZ to Sioux Falls, SD: