There are 327.52 miles from Milwaukee to Saint Louis in southwest direction and 373 miles (600.29 kilometers) by car, following the I-55 route.
Milwaukee and Saint Louis are 6 hours 57 mins far apart, if you drive non-stop.
This is the fastest route from Milwaukee, WI to Saint Louis, MO. The halfway point is Lexington, IL.
Milwaukee, WI and Saint Louis, MO are in the same time zone (Central Daylight Time). Current time in both locations is 8:02 pm.
Any questions or tips to share?
Share with fellow travellers any question or tips about the route from Milwaukee, WI to Saint Louis, MO: