There are 60.66 miles from Murphy to Knoxville in north direction and 103 miles (165.76 kilometers) by car, following the SR 68 route.
Murphy and Knoxville are 2 hours 14 mins far apart, if you drive non-stop .
This is the fastest route from Murphy, NC to Knoxville, TN. The halfway point is Madisonville, TN.
Murphy, NC and Knoxville, TN are in the same time zone (EDT). Current time in both locations is 6:13 pm.
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