There are 841.92 miles from Neillsville to Carlisle in southeast direction and 1,045 miles (1,681.76 kilometers) by car, following the I-64 E route.
Neillsville and Carlisle are 17 hours 2 mins far apart, if you drive non-stop .
This is the fastest route from Neillsville, WI to Carlisle, SC. The halfway point is Edinburgh, IN.
Please note the time difference between Neillsville, WI and Carlisle, SC is 1 hour. The current time in Neillsville is 6:41 am and the current time in Carlisle is 7:41 am.
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