There are 281.06 miles from O'Hare International Airport (ORD) to Louisville in southeast direction and 313 miles (503.72 kilometers) by car, following the I-65 S route.
ORD Airport and Louisville are 5 hours 23 mins far apart, if you drive non-stop .
This is the fastest route from ORD Airport to Louisville, KY. The halfway point is Clarks Hill, IN.
Please note the time difference between ORD Airport and Louisville, KY is 1 hour. The current time in ORD Airport is 9:34 am and the current time in Louisville is 10:34 am.
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