There are 107.37 miles from Orlando to Port Saint Lucie in southeast direction and 125 miles (201.17 kilometers) by car, following the Florida's Turnpike route.
Orlando and Port Saint Lucie are 2 hours 19 mins far apart, if you drive non-stop.
This is the fastest route from Orlando, FL to Port Saint Lucie, FL. The halfway point is Kenansville, FL.
Orlando, FL and Port Saint Lucie, FL are in the same time zone (Eastern Daylight Time). Current time in both locations is 2:10 pm.
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