There are 551.22 miles from Philadelphia to Knoxville in southwest direction and 625.96 miles by car, following the route.
Philadelphia and Knoxville are 9 hours 21 mins far apart, if you drive non-stop.
This is the fastest route from Philadelphia, PA to Knoxville, TN. The halfway point is .
Philadelphia, PA and Knoxville, TN are in the same time zone (EDT). Current time in both locations is 9:04 am.
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