There are 1,488.07 miles from Pine River to Big Pine Key in southeast direction and 1,815 miles (2,920.96 kilometers) by car, following the I-75 S route.
Pine River and Big Pine Key are 1 day 3 hours far apart, if you drive non-stop .
This is the fastest route from Pine River, WI to Big Pine Key, FL. The halfway point is Whiteside, TN.
Please note the time difference between Pine River, WI and Big Pine Key, FL is 1 hour. The current time in Pine River is 4:13 am and the current time in Big Pine Key is 5:13 am.
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