There are 322.71 miles from Port Saint Lucie to Tallahassee in northwest direction and 370 miles (595.46 kilometers) by car, following the Florida's Turnpike route.
Port Saint Lucie and Tallahassee are 6 hours 45 mins far apart, if you drive non-stop.
This is the fastest route from Port Saint Lucie, FL to Tallahassee, FL. The halfway point is Ocala, FL.
Port Saint Lucie, FL and Tallahassee, FL are in the same time zone (Eastern Daylight Time). Current time in both locations is 9:35 pm.
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