There are 493.46 miles from Reno to San Diego in southeast direction and 558 miles (898.01 kilometers) by car, following the US-395 route.
Reno and San Diego are 11 hours 19 mins far apart, if you drive non-stop.
This is the fastest route from Reno, NV to San Diego, CA. The halfway point is Cartago, CA.
Reno, NV and San Diego, CA are in the same time zone (Pacific Daylight Time). Current time in both locations is 10:02 pm.
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