There are 314.43 miles from Ripley to Knoxville in east direction and 353 miles (568.10 kilometers) by car, following the I-40 route.
Ripley and Knoxville are 5 hours 37 mins far apart, if you drive non-stop .
This is the fastest route from Ripley, TN to Knoxville, TN. The halfway point is Nashville, TN.
Please note the time difference between Ripley, TN and Knoxville, TN is 1 hour. The current time in Ripley is 8:59 am and the current time in Knoxville is 9:59 am.
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